Cross-Protection against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and Protein

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory illness and has a high mortality of ∼34%. However, since its discovery in 2012, an effective vaccine has not been developed for it. To develop a vaccine against multiple strains of MERS-CoV, we targeted spike glycoprot...

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Detalles Bibliográficos
Autores principales: Choi, Jung-ah, Goo, Junghyun, Yang, Eunji, Jung, Dae-Im, Lee, Sena, Rho, Semi, Jeong, Yuji, Park, Young-Shin, Park, Hayan, Moon, Young-hye, Park, Uni, Seo, Sang-Hwan, Lee, Hyeja, Lee, Jae Myun, Cho, Nam-Hyuk, Song, Manki, Kim, Jae-Ouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925194/
https://www.ncbi.nlm.nih.gov/pubmed/32967955
http://dx.doi.org/10.1128/JVI.01176-20

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