The Epigenetic Regulator EZH2 Instructs CD4 T Cell Response to Acute Viral Infection via Coupling of Cell Expansion and Metabolic Fitness

The protection of a majority of viral vaccines is mediated by CD4 T cell-dependent humoral immunity. The methyltransferase enhancer of zeste homolog 2 (EZH2) dictates the differentiation of naive CD4 T cells into distinct effector T helper subsets at the onset of acute viral infection. However, whet...

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Detalles Bibliográficos
Autores principales: Li, Ren, Pan, Zhiwei, Wu, Jialin, Yue, Shuai, Lin, Yao, Yang, Yang, Li, Zhirong, Hu, Li, Tang, Jianfang, Shan, Lingling, Tian, Qin, Jiang, Peng, Wei, Ping, Ye, Lilin, Liu, Pinghuang, Chen, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Cellular Response to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925195/
https://www.ncbi.nlm.nih.gov/pubmed/32999031
http://dx.doi.org/10.1128/JVI.01627-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925195/
https://www.ncbi.nlm.nih.gov/pubmed/32999031
http://dx.doi.org/10.1128/JVI.01627-20

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