Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom

A 74-year-old man presented with abdominal swelling. Computed tomography revealed massive ascites and localized thickening of the small intestinal wall. Enteroscopy showed ulcerative lesions along the circumference of the jejunum. Histological examination showed dense proliferation of large lymphoid...

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Autores principales: Ota, Kazuhiro, Nishida, Shinya, Akutagawa, Hiroshi, Imai, Yoshiro, Tani, Kiri, Shinohara, Yoshinori, Iwatsubo, Taro, Shimpei, Kawaguchi, Kojima, Yuichi, Takeuchi, Toshihisa, Higuchi, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925287/
https://www.ncbi.nlm.nih.gov/pubmed/32863368
http://dx.doi.org/10.2169/internalmedicine.5516-20
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author Ota, Kazuhiro
Nishida, Shinya
Akutagawa, Hiroshi
Imai, Yoshiro
Tani, Kiri
Shinohara, Yoshinori
Iwatsubo, Taro
Shimpei, Kawaguchi
Kojima, Yuichi
Takeuchi, Toshihisa
Higuchi, Kazuhide
author_facet Ota, Kazuhiro
Nishida, Shinya
Akutagawa, Hiroshi
Imai, Yoshiro
Tani, Kiri
Shinohara, Yoshinori
Iwatsubo, Taro
Shimpei, Kawaguchi
Kojima, Yuichi
Takeuchi, Toshihisa
Higuchi, Kazuhide
author_sort Ota, Kazuhiro
collection PubMed
description A 74-year-old man presented with abdominal swelling. Computed tomography revealed massive ascites and localized thickening of the small intestinal wall. Enteroscopy showed ulcerative lesions along the circumference of the jejunum. Histological examination showed dense proliferation of large lymphoid atypical cells, and immunohistochemistry showed CD20 and CD10 positivity, CD3 negativity, and Ki67 labeling index >80%. Cytology of the ascitic fluid revealed large lymphoid cells. These findings suggest that small intestine primary diffuse large B-cell lymphoma (DLBCL) caused the ascites. Massive ascites as an initial symptom of primary DLBCL of the jejunum is rare. Herein, we describe this unusual presentation.
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spelling pubmed-79252872021-03-10 Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom Ota, Kazuhiro Nishida, Shinya Akutagawa, Hiroshi Imai, Yoshiro Tani, Kiri Shinohara, Yoshinori Iwatsubo, Taro Shimpei, Kawaguchi Kojima, Yuichi Takeuchi, Toshihisa Higuchi, Kazuhide Intern Med Case Report A 74-year-old man presented with abdominal swelling. Computed tomography revealed massive ascites and localized thickening of the small intestinal wall. Enteroscopy showed ulcerative lesions along the circumference of the jejunum. Histological examination showed dense proliferation of large lymphoid atypical cells, and immunohistochemistry showed CD20 and CD10 positivity, CD3 negativity, and Ki67 labeling index >80%. Cytology of the ascitic fluid revealed large lymphoid cells. These findings suggest that small intestine primary diffuse large B-cell lymphoma (DLBCL) caused the ascites. Massive ascites as an initial symptom of primary DLBCL of the jejunum is rare. Herein, we describe this unusual presentation. The Japanese Society of Internal Medicine 2020-08-29 2021-02-01 /pmc/articles/PMC7925287/ /pubmed/32863368 http://dx.doi.org/10.2169/internalmedicine.5516-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ota, Kazuhiro
Nishida, Shinya
Akutagawa, Hiroshi
Imai, Yoshiro
Tani, Kiri
Shinohara, Yoshinori
Iwatsubo, Taro
Shimpei, Kawaguchi
Kojima, Yuichi
Takeuchi, Toshihisa
Higuchi, Kazuhide
Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title_full Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title_fullStr Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title_full_unstemmed Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title_short Massive Ascites Caused by Primary Diffuse Large B-cell Lymphoma of the Jejunum: A Case of a Rare Initial Symptom
title_sort massive ascites caused by primary diffuse large b-cell lymphoma of the jejunum: a case of a rare initial symptom
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925287/
https://www.ncbi.nlm.nih.gov/pubmed/32863368
http://dx.doi.org/10.2169/internalmedicine.5516-20
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