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Astragaloside IV inhibits palmitic acid-induced apoptosis through regulation of calcium homeostasis in mice podocytes
Loss of podocytes is a hallmark of diabetic nephropathy, and a growing body of evidence indicates that podocytes are susceptible to palmitic acid (PA). We have previously shown that AS-IV inhibited PA-induced podocyte apoptosis by activating sarcoendoplasmic reticulum Ca(2+) ATPase (SERCA), which in...
Autores principales: | Zang, Yingjun, Liu, Shuang, Cao, Aili, Shan, Xiangyu, Deng, Wenjuan, Li, Zhijun, Wang, Hao, Wang, Yunman, Wang, Li, Peng, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925475/ https://www.ncbi.nlm.nih.gov/pubmed/33606151 http://dx.doi.org/10.1007/s11033-021-06204-4 |
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