RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming

N6-methyladenosine (m6A) is a reversible mRNA modification that has been shown to play important roles in various biological processes. However, the roles of m6A modification in macrophages are still unknown. Here, we discover that ablation of Mettl3 in myeloid cells promotes tumour growth and metas...

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Detalles Bibliográficos
Autores principales: Yin, Huilong, Zhang, Xiang, Yang, Pengyuan, Zhang, Xiaofang, Peng, Yingran, Li, Da, Yu, Yanping, Wu, Ye, Wang, Yidi, Zhang, Jinbao, Ding, Xiaochen, Wang, Xiangpeng, Yang, Angang, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925544/
https://www.ncbi.nlm.nih.gov/pubmed/33654093
http://dx.doi.org/10.1038/s41467-021-21514-8

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