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Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences
Increasing numbers of protein interactions have been identified in high-throughput experiments, but only a small proportion have solved structures. Recently, sequence coevolution-based approaches have led to a breakthrough in predicting monomer protein structures and protein interaction interfaces....
Autores principales: | Green, Anna G., Elhabashy, Hadeer, Brock, Kelly P., Maddamsetti, Rohan, Kohlbacher, Oliver, Marks, Debora S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925567/ https://www.ncbi.nlm.nih.gov/pubmed/33654096 http://dx.doi.org/10.1038/s41467-021-21636-z |
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