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Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences

Increasing numbers of protein interactions have been identified in high-throughput experiments, but only a small proportion have solved structures. Recently, sequence coevolution-based approaches have led to a breakthrough in predicting monomer protein structures and protein interaction interfaces....

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Detalles Bibliográficos
Autores principales: Green, Anna G., Elhabashy, Hadeer, Brock, Kelly P., Maddamsetti, Rohan, Kohlbacher, Oliver, Marks, Debora S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925567/
https://www.ncbi.nlm.nih.gov/pubmed/33654096
http://dx.doi.org/10.1038/s41467-021-21636-z

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