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APOE and Alzheimer’s Disease: From Lipid Transport to Physiopathology and Therapeutics
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations. One risk factor for developing AD is the APOE gene coding for the apolipoprotein E protein (apoE). Humans have three versions of APOE gene: ε...
Autores principales: | Husain, Mohammed Amir, Laurent, Benoit, Plourde, Mélanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925634/ https://www.ncbi.nlm.nih.gov/pubmed/33679311 http://dx.doi.org/10.3389/fnins.2021.630502 |
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