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Complete biosynthesis of a sulfated chondroitin in Escherichia coli
Sulfated glycosaminoglycans (GAGs) are a class of important biologics that are currently manufactured by extraction from animal tissues. Although such methods are unsustainable and prone to contamination, animal-free production methods have not emerged as competitive alternatives due to complexities...
Autores principales: | Badri, Abinaya, Williams, Asher, Awofiranye, Adeola, Datta, Payel, Xia, Ke, He, Wenqin, Fraser, Keith, Dordick, Jonathan S., Linhardt, Robert J., Koffas, Mattheos A. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925653/ https://www.ncbi.nlm.nih.gov/pubmed/33654100 http://dx.doi.org/10.1038/s41467-021-21692-5 |
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