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Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment

To clip or coil has been matter of debates for several years and is the domain of interdisciplinary decision making. However, the microsurgical outcome has still been elusive concerning wide neck aneurysms (WNA). A retrospective single center study was performed with all patients with ruptured WNA (...

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Autores principales: Won, Sae-Yeon, Seifert, Volker, Dubinski, Daniel, Kashefiolasl, Sepide, Dinc, Nazife, Bruder, Markus, Konczalla, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925666/
https://www.ncbi.nlm.nih.gov/pubmed/33654126
http://dx.doi.org/10.1038/s41598-021-84339-x
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author Won, Sae-Yeon
Seifert, Volker
Dubinski, Daniel
Kashefiolasl, Sepide
Dinc, Nazife
Bruder, Markus
Konczalla, Juergen
author_facet Won, Sae-Yeon
Seifert, Volker
Dubinski, Daniel
Kashefiolasl, Sepide
Dinc, Nazife
Bruder, Markus
Konczalla, Juergen
author_sort Won, Sae-Yeon
collection PubMed
description To clip or coil has been matter of debates for several years and is the domain of interdisciplinary decision making. However, the microsurgical outcome has still been elusive concerning wide neck aneurysms (WNA). A retrospective single center study was performed with all patients with ruptured WNA (rWNA) and unruptured WNA (uWNA) admitted to author´s institute between 2007–2017. Microsurgical outcome was evaluated according to Raymond-Roy occlusion grade and follow-up angiography was performed to analyze the stability of neck/aneurysm remnants and retreatment poverty. Of 805 aneurysms, 139 were rWNA (17.3%) and 148 uWNA (18.4%). Complete occlusion was achieved in 102 of 139 rWNA (73.4%) and 112 of 148 uWNA (75.6%). Neck remnants were observed in 36 patients with rWNA (25.9%) and 30 patients with uWNA (20.3%), 1 (0.7%) and 6 (4.1%) patients had aneurysmal remnant, respectively. Overall complication rate was 11.5%. At follow-up (939/1504 months), all remnants were stable except for one, which was further conservatively treated with marginal retreatment rate under 1%. Even the risk of de-novo aneurysm was higher than the risk for remnant growth (2.6% vs 0% in rWNA; 8.7% vs 5.3% in uWNA) without significant difference. Microsurgical clipping is effective for complete occlusion of r/uWNA with low complication. Furthermore, the risk of remnant growth is marginal even lower than the risk of de-novo rate low retreatment rate.
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spelling pubmed-79256662021-03-04 Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment Won, Sae-Yeon Seifert, Volker Dubinski, Daniel Kashefiolasl, Sepide Dinc, Nazife Bruder, Markus Konczalla, Juergen Sci Rep Article To clip or coil has been matter of debates for several years and is the domain of interdisciplinary decision making. However, the microsurgical outcome has still been elusive concerning wide neck aneurysms (WNA). A retrospective single center study was performed with all patients with ruptured WNA (rWNA) and unruptured WNA (uWNA) admitted to author´s institute between 2007–2017. Microsurgical outcome was evaluated according to Raymond-Roy occlusion grade and follow-up angiography was performed to analyze the stability of neck/aneurysm remnants and retreatment poverty. Of 805 aneurysms, 139 were rWNA (17.3%) and 148 uWNA (18.4%). Complete occlusion was achieved in 102 of 139 rWNA (73.4%) and 112 of 148 uWNA (75.6%). Neck remnants were observed in 36 patients with rWNA (25.9%) and 30 patients with uWNA (20.3%), 1 (0.7%) and 6 (4.1%) patients had aneurysmal remnant, respectively. Overall complication rate was 11.5%. At follow-up (939/1504 months), all remnants were stable except for one, which was further conservatively treated with marginal retreatment rate under 1%. Even the risk of de-novo aneurysm was higher than the risk for remnant growth (2.6% vs 0% in rWNA; 8.7% vs 5.3% in uWNA) without significant difference. Microsurgical clipping is effective for complete occlusion of r/uWNA with low complication. Furthermore, the risk of remnant growth is marginal even lower than the risk of de-novo rate low retreatment rate. Nature Publishing Group UK 2021-03-02 /pmc/articles/PMC7925666/ /pubmed/33654126 http://dx.doi.org/10.1038/s41598-021-84339-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Won, Sae-Yeon
Seifert, Volker
Dubinski, Daniel
Kashefiolasl, Sepide
Dinc, Nazife
Bruder, Markus
Konczalla, Juergen
Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title_full Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title_fullStr Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title_full_unstemmed Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title_short Short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
title_sort short- and midterm outcome of ruptured and unruptured intracerebral wide-necked aneurysms with microsurgical treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925666/
https://www.ncbi.nlm.nih.gov/pubmed/33654126
http://dx.doi.org/10.1038/s41598-021-84339-x
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