Delayed contrast enhancement of hepatic parenchyma after intravenous sonographic contrast agent: unusual phenomenon. Case report and review of literature

AIM: A case of heterogeneous late-phase hepatic enhancement (HLHE) using contrast‐enhanced ultrasound (CEUS) with SonoVue is presented, where HLHE lasted after 50 min of injection. METHODS: This study aims to review prior literature on this topic, to characterize the features of HLHE in the liver, a...

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Detalles Bibliográficos
Autores principales: Tarnoki, David Laszlo, Tarnoki, Adam Domonkos, Sukosd, Hunor, Folhoffer, Aniko, Harkanyi, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925801/
https://www.ncbi.nlm.nih.gov/pubmed/31981154
http://dx.doi.org/10.1007/s40477-020-00429-y
Descripción
Sumario:AIM: A case of heterogeneous late-phase hepatic enhancement (HLHE) using contrast‐enhanced ultrasound (CEUS) with SonoVue is presented, where HLHE lasted after 50 min of injection. METHODS: This study aims to review prior literature on this topic, to characterize the features of HLHE in the liver, and to find possible and reliable explanations for this phenomenon. RESULTS: From literature, thus far five publications discuss this phenomenon with a total of 21 patients. CONCLUSION: We suggest that phagocytosis of contrast agent microbubbles by macrophages, and lymphocytosis of peripheral blood due to stress conditions of the patients might be in the background of HLHE.

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