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The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington’s Disease Mice
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an early and central disease mechanism which is accompanied by epigenetic alterations in HD. Previous st...
Autores principales: | Hecklau, Katharina, Mueller, Susanne, Koch, Stefan Paul, Mehkary, Mustafa Hussain, Kilic, Busra, Harms, Christoph, Boehm-Sturm, Philipp, Yildirim, Ferah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925995/ https://www.ncbi.nlm.nih.gov/pubmed/33679321 http://dx.doi.org/10.3389/fnmol.2021.616886 |
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