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Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature
Locus minoris resistentiae refers to a region of decreased resistance within the body. This occurs from changes to the microenvironment secondary to previous trauma and results in increased vulnerability. As a result, infection, inflammatory processes, and malignancy may localize to this area. In th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926049/ https://www.ncbi.nlm.nih.gov/pubmed/33629603 http://dx.doi.org/10.1177/2324709621997248 |
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author | Farmand, Donya Valdez, Michael C. Moosavi, Leila Cobos, Everardo |
author_facet | Farmand, Donya Valdez, Michael C. Moosavi, Leila Cobos, Everardo |
author_sort | Farmand, Donya |
collection | PubMed |
description | Locus minoris resistentiae refers to a region of decreased resistance within the body. This occurs from changes to the microenvironment secondary to previous trauma and results in increased vulnerability. As a result, infection, inflammatory processes, and malignancy may localize to this area. In this article, we describe 2 unique cases of malignancy, primary prostate carcinoma and serous carcinoma of the ovary, both of which disseminated to sites of prior trauma. We review the available literature, discuss proposed pathophysiology, and highlight the need for further investigations along with increased clinician awareness. |
format | Online Article Text |
id | pubmed-7926049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-79260492021-03-11 Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature Farmand, Donya Valdez, Michael C. Moosavi, Leila Cobos, Everardo J Investig Med High Impact Case Rep Case Report Locus minoris resistentiae refers to a region of decreased resistance within the body. This occurs from changes to the microenvironment secondary to previous trauma and results in increased vulnerability. As a result, infection, inflammatory processes, and malignancy may localize to this area. In this article, we describe 2 unique cases of malignancy, primary prostate carcinoma and serous carcinoma of the ovary, both of which disseminated to sites of prior trauma. We review the available literature, discuss proposed pathophysiology, and highlight the need for further investigations along with increased clinician awareness. SAGE Publications 2021-02-25 /pmc/articles/PMC7926049/ /pubmed/33629603 http://dx.doi.org/10.1177/2324709621997248 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Farmand, Donya Valdez, Michael C. Moosavi, Leila Cobos, Everardo Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title | Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title_full | Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title_fullStr | Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title_full_unstemmed | Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title_short | Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature |
title_sort | locus minoris resistentiae: two cases of malignant metastasis and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926049/ https://www.ncbi.nlm.nih.gov/pubmed/33629603 http://dx.doi.org/10.1177/2324709621997248 |
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