Duration of Viral Clearance in Children With SARS-CoV-2 Infection in Rajasthan, India

OBJECTIVE: To study the clinical and laboratory profile and to assess period for viral clearance in COVID 19 children. METHODS: We reviewed hospital records of children (<18 years) admitted from 1 April to 31 May, 2020 at a tertiary-care public hospital and identified those positive for severe ac...

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Detalles Bibliográficos
Autores principales: Gupta, Manohar Lal, Gothwal, Sunil, Gupta, Raj Kumar, Sharma, Ram Babu, Meena, Jeetam Singh, Sulaniya, Pawan Kumar, Dev, Deveshwar, Gupta, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926061/
https://www.ncbi.nlm.nih.gov/pubmed/33257599
http://dx.doi.org/10.1007/s13312-021-2125-6
Descripción
Sumario:OBJECTIVE: To study the clinical and laboratory profile and to assess period for viral clearance in COVID 19 children. METHODS: We reviewed hospital records of children (<18 years) admitted from 1 April to 31 May, 2020 at a tertiary-care public hospital and identified those positive for severe acute respiratory syndrome corona virus (SARS-CoV-2) by RT-PCR of respiratory secretions. RESULTS: 81.2% of the 85 children studied were asymptomatic and 3 (8.5%) died. Severe lymphopenia (43.8%), raised C-reactive protein (93.8%), raised erythrocyte sedimentation rate (75%) and high (>500ng/mL) levels of D-dimer (37.5%) were common. Median (IQR) duration of viral shedding was 7 (5–10) days, with range of 2 to 45 days; 96.3% had viral clearance within 14 days. CONCLUSIONS: Majority of children aged <18 years with SARS-CoV-2 infection had viral clearance within 14 days.

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