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Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells

A major challenge to tuberculosis (TB) vaccine development is the lack of a validated immune correlate of protection. Mycobacterial growth inhibition assays (MGIAs) represent an unbiased measure of the ability to control mycobacterial growth in vitro. A successful MGIA could be applied to preclinica...

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Detalles Bibliográficos
Autores principales:	Tanner, Rachel, Smith, Steven G., van Meijgaarden, Krista E., Giannoni, Federico, Wilkie, Morven, Gabriele, Lucia, Palma, Carla, Dockrell, Hazel M., Ottenhoff, Tom H.M., McShane, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926177/ https://www.ncbi.nlm.nih.gov/pubmed/30710562 http://dx.doi.org/10.1016/j.jim.2019.01.006

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