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Modeling by disruption and a selected‐for partner for the nude locus

A long‐standing problem in biology is how to dissect traits for which no tractable model exists. Here, we screen for genes like the nude locus (Foxn1)—genes central to mammalian hair and thymus development—using animals that never evolved hair, thymi, or Foxn1. Fruit flies are morphologically disrup...

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Detalles Bibliográficos
Autores principales: Li, Jian, Lee, Yun‐Kyoung, Fu, Wenyu, Whalen, Anne M, Estable, Mario C, Raftery, Laurel A, White, Kristin, Weiner, Lorin, Brissette, Janice L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926259/
https://www.ncbi.nlm.nih.gov/pubmed/33369874
http://dx.doi.org/10.15252/embr.201949804