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EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning
EDEM3 recognizes and directs misfolded proteins to the ER-associated protein degradation (ERAD) process. EDEM3 was predicted to act as lectin or as a mannosidase because of its homology with the GH47 catalytic domain of the Man1B1, but the contribution of the other regions remained unresolved. Here,...
Autores principales: | Manica, Georgiana, Ghenea, Simona, Munteanu, Cristian V. A., Martin, Eliza C., Butnaru, Cristian, Surleac, Marius, Chiritoiu, Gabriela N., Alexandru, Petruta R., Petrescu, Andrei-Jose, Petrescu, Stefana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926307/ https://www.ncbi.nlm.nih.gov/pubmed/33671632 http://dx.doi.org/10.3390/ijms22042172 |
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