NQO1 Deficiency Aggravates Renal Injury by Dysregulating Vps34/ATG14L Complex during Autophagy Initiation in Diabetic Nephropathy

Diabetic nephropathy (DN) is one of the causes of end-stage renal failure, featuring renal fibrosis. However, autophagy, a vital process for intracellular homeostasis, can counteract renal fibrosis. Moreover, NAD(P)H: quinone dehydrogenase 1 (NQO1) modulates the ratios of reduced/oxidized nicotinami...

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Detalles Bibliográficos
Autores principales: Hong, Geum-Lan, Kim, Kyung-Hyun, Lee, Chul-Ho, Kim, Tae-Won, Jung, Ju-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926338/
https://www.ncbi.nlm.nih.gov/pubmed/33672316
http://dx.doi.org/10.3390/antiox10020333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926338/
https://www.ncbi.nlm.nih.gov/pubmed/33672316
http://dx.doi.org/10.3390/antiox10020333

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