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Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding

Parasitic organisms especially those of the Apicomplexan phylum, harbour a cytosol localised canonical Hsp70 chaperone. One of the defining features of this protein is the presence of GGMP repeat residues sandwiched between α-helical lid and C-terminal EEVD motif. The role of the GGMP repeats of Hsp...

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Detalles Bibliográficos
Autores principales:	Makumire, Stanley, Dongola, Tendamudzimu Harmfree, Chakafana, Graham, Tshikonwane, Lufuno, Chauke, Cecilia Tshikani, Maharaj, Tarushai, Zininga, Tawanda, Shonhai, Addmore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926355/ https://www.ncbi.nlm.nih.gov/pubmed/33672387 http://dx.doi.org/10.3390/ijms22042226

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