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The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders

Background: Due to the potentially crucial role of vitamin K(2) in calcium metabolism, a deficit can disrupt many mechanisms, resulting in an array of different issues, such as broken bones, stiff arteries and poor fertility. Although there has been existing research, the potential of vitamin K(2) a...

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Autores principales: Khalil, Zeyad, Alam, Benyamin, Akbari, Amir Reza, Sharma, Harbans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926526/
https://www.ncbi.nlm.nih.gov/pubmed/33670005
http://dx.doi.org/10.3390/nu13020691
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author Khalil, Zeyad
Alam, Benyamin
Akbari, Amir Reza
Sharma, Harbans
author_facet Khalil, Zeyad
Alam, Benyamin
Akbari, Amir Reza
Sharma, Harbans
author_sort Khalil, Zeyad
collection PubMed
description Background: Due to the potentially crucial role of vitamin K(2) in calcium metabolism, a deficit can disrupt many mechanisms, resulting in an array of different issues, such as broken bones, stiff arteries and poor fertility. Although there has been existing research, the potential of vitamin K(2) as a treatment for conditions including cerebral palsy, parathyroid disease, heart disease and gastrointestinal disease is unknown. This review discusses the biochemistry of vitamin K and the metabolism of calcium, followed by an analysis of the current literature available on vitamin K(2) and its prospects. Methods: Using public libraries including PubMed and Wiley, we searched for existing research on the metabolism and use of vitamin K(2) that has been conducted in the preceding two decades. Results: Data indicated that vitamin K(2) had a positive impact on osteoporosis, cardiovascular disease, parathyroid disorders, cerebral palsy and sperm motility. Conclusion: Due to the existence of confounding variables and limitations in the quality and volume of research conducted, further investigation must be done to see whether the beneficial effects seen are reproducible and must assess the viability of vitamin K(2) as treatment in isolation for these conditions.
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spelling pubmed-79265262021-03-04 The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders Khalil, Zeyad Alam, Benyamin Akbari, Amir Reza Sharma, Harbans Nutrients Review Background: Due to the potentially crucial role of vitamin K(2) in calcium metabolism, a deficit can disrupt many mechanisms, resulting in an array of different issues, such as broken bones, stiff arteries and poor fertility. Although there has been existing research, the potential of vitamin K(2) as a treatment for conditions including cerebral palsy, parathyroid disease, heart disease and gastrointestinal disease is unknown. This review discusses the biochemistry of vitamin K and the metabolism of calcium, followed by an analysis of the current literature available on vitamin K(2) and its prospects. Methods: Using public libraries including PubMed and Wiley, we searched for existing research on the metabolism and use of vitamin K(2) that has been conducted in the preceding two decades. Results: Data indicated that vitamin K(2) had a positive impact on osteoporosis, cardiovascular disease, parathyroid disorders, cerebral palsy and sperm motility. Conclusion: Due to the existence of confounding variables and limitations in the quality and volume of research conducted, further investigation must be done to see whether the beneficial effects seen are reproducible and must assess the viability of vitamin K(2) as treatment in isolation for these conditions. MDPI 2021-02-21 /pmc/articles/PMC7926526/ /pubmed/33670005 http://dx.doi.org/10.3390/nu13020691 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Khalil, Zeyad
Alam, Benyamin
Akbari, Amir Reza
Sharma, Harbans
The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title_full The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title_fullStr The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title_full_unstemmed The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title_short The Medical Benefits of Vitamin K(2) on Calcium-Related Disorders
title_sort medical benefits of vitamin k(2) on calcium-related disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926526/
https://www.ncbi.nlm.nih.gov/pubmed/33670005
http://dx.doi.org/10.3390/nu13020691
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