Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets

SIMPLE SUMMARY: Recently, our understanding of PFK-2 isozymes, particularly with regards to their roles in cancer, has developed significantly. This review aims to compile the most crucial achievements in this field. Due to the prevailing number of recent studies on PFKFB3 and PFKFB4, we mainly focu...

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Detalles Bibliográficos
Autores principales: Kotowski, Krzysztof, Rosik, Jakub, Machaj, Filip, Supplitt, Stanisław, Wiczew, Daniel, Jabłońska, Karolina, Wiechec, Emilia, Ghavami, Saeid, Dzięgiel, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926708/
https://www.ncbi.nlm.nih.gov/pubmed/33671514
http://dx.doi.org/10.3390/cancers13040909

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