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Cell-Free DNA Fragments as Biomarkers of Islet β-Cell Death in Obesity and Type 2 Diabetes
Type 2 diabetes (T2D) typically occurs in the setting of obesity and insulin resistance, where hyperglycemia is associated with decreased pancreatic β-cell mass and function. Loss of β-cell mass has variably been attributed to β-cell dedifferentiation and/or death. In recent years, it has been propo...
Autores principales: | Arosemena, Marilyn, Meah, Farah A., Mather, Kieren J., Tersey, Sarah A., Mirmira, Raghavendra G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926743/ https://www.ncbi.nlm.nih.gov/pubmed/33670079 http://dx.doi.org/10.3390/ijms22042151 |
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