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RNase A Domain-Swapped Dimers Produced Through Different Methods: Structure–Catalytic Properties and Antitumor Activity

Upon oligomerization, RNase A can acquire important properties, such as cytotoxicity against leukemic cells. When lyophilized from 40% acetic acid solutions, the enzyme self-associates through the so-called three-dimensional domain swapping (3D-DS) mechanism involving both N- and/or C-terminals. The...

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Detalles Bibliográficos
Autores principales:	Montioli, Riccardo, Campagnari, Rachele, Fasoli, Sabrina, Fagagnini, Andrea, Caloiu, Andra, Smania, Marcello, Menegazzi, Marta, Gotte, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926746/ https://www.ncbi.nlm.nih.gov/pubmed/33669993 http://dx.doi.org/10.3390/life11020168

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