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Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications

The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and...

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Autores principales: Montaño-Machado, Vanessa, Chevallier, Pascale, Bonilla-Gameros, Linda, Copes, Francesco, Quarta, Chiara, Kú-Herrera, José de Jesús, Soriano, Florentino, Padilla-Gainza, Victoria, Morales, Graciela, Mantovani, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926823/
https://www.ncbi.nlm.nih.gov/pubmed/33672249
http://dx.doi.org/10.3390/ma14041047
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author Montaño-Machado, Vanessa
Chevallier, Pascale
Bonilla-Gameros, Linda
Copes, Francesco
Quarta, Chiara
Kú-Herrera, José de Jesús
Soriano, Florentino
Padilla-Gainza, Victoria
Morales, Graciela
Mantovani, Diego
author_facet Montaño-Machado, Vanessa
Chevallier, Pascale
Bonilla-Gameros, Linda
Copes, Francesco
Quarta, Chiara
Kú-Herrera, José de Jesús
Soriano, Florentino
Padilla-Gainza, Victoria
Morales, Graciela
Mantovani, Diego
author_sort Montaño-Machado, Vanessa
collection PubMed
description The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications.
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spelling pubmed-79268232021-03-04 Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications Montaño-Machado, Vanessa Chevallier, Pascale Bonilla-Gameros, Linda Copes, Francesco Quarta, Chiara Kú-Herrera, José de Jesús Soriano, Florentino Padilla-Gainza, Victoria Morales, Graciela Mantovani, Diego Materials (Basel) Article The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications. MDPI 2021-02-23 /pmc/articles/PMC7926823/ /pubmed/33672249 http://dx.doi.org/10.3390/ma14041047 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Montaño-Machado, Vanessa
Chevallier, Pascale
Bonilla-Gameros, Linda
Copes, Francesco
Quarta, Chiara
Kú-Herrera, José de Jesús
Soriano, Florentino
Padilla-Gainza, Victoria
Morales, Graciela
Mantovani, Diego
Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title_full Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title_fullStr Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title_full_unstemmed Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title_short Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
title_sort development of multifunctional materials based on poly(ether ether ketone) with improved biological performances for dental applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926823/
https://www.ncbi.nlm.nih.gov/pubmed/33672249
http://dx.doi.org/10.3390/ma14041047
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