Cargando…
Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications
The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926823/ https://www.ncbi.nlm.nih.gov/pubmed/33672249 http://dx.doi.org/10.3390/ma14041047 |
_version_ | 1783659550827610112 |
---|---|
author | Montaño-Machado, Vanessa Chevallier, Pascale Bonilla-Gameros, Linda Copes, Francesco Quarta, Chiara Kú-Herrera, José de Jesús Soriano, Florentino Padilla-Gainza, Victoria Morales, Graciela Mantovani, Diego |
author_facet | Montaño-Machado, Vanessa Chevallier, Pascale Bonilla-Gameros, Linda Copes, Francesco Quarta, Chiara Kú-Herrera, José de Jesús Soriano, Florentino Padilla-Gainza, Victoria Morales, Graciela Mantovani, Diego |
author_sort | Montaño-Machado, Vanessa |
collection | PubMed |
description | The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications. |
format | Online Article Text |
id | pubmed-7926823 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79268232021-03-04 Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications Montaño-Machado, Vanessa Chevallier, Pascale Bonilla-Gameros, Linda Copes, Francesco Quarta, Chiara Kú-Herrera, José de Jesús Soriano, Florentino Padilla-Gainza, Victoria Morales, Graciela Mantovani, Diego Materials (Basel) Article The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications. MDPI 2021-02-23 /pmc/articles/PMC7926823/ /pubmed/33672249 http://dx.doi.org/10.3390/ma14041047 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Montaño-Machado, Vanessa Chevallier, Pascale Bonilla-Gameros, Linda Copes, Francesco Quarta, Chiara Kú-Herrera, José de Jesús Soriano, Florentino Padilla-Gainza, Victoria Morales, Graciela Mantovani, Diego Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title | Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title_full | Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title_fullStr | Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title_full_unstemmed | Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title_short | Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications |
title_sort | development of multifunctional materials based on poly(ether ether ketone) with improved biological performances for dental applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926823/ https://www.ncbi.nlm.nih.gov/pubmed/33672249 http://dx.doi.org/10.3390/ma14041047 |
work_keys_str_mv | AT montanomachadovanessa developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT chevallierpascale developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT bonillagameroslinda developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT copesfrancesco developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT quartachiara developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT kuherrerajosedejesus developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT sorianoflorentino developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT padillagainzavictoria developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT moralesgraciela developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications AT mantovanidiego developmentofmultifunctionalmaterialsbasedonpolyetheretherketonewithimprovedbiologicalperformancesfordentalapplications |