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Versatile Use of Chitosan and Hyaluronan in Medicine †

Chitosan is industrially acquired by the alkaline N-deacetylation of chitin. Chitin belongs to the β-N-acetyl-glucosamine polymers, providing structure, contrary to α-polymers, which provide food and energy. Another β-polymer providing structure is hyaluronan. A lot of studies have been performed on...

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Detalles Bibliográficos
Autores principales: Valachová, Katarína, Šoltés, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926841/
https://www.ncbi.nlm.nih.gov/pubmed/33672365
http://dx.doi.org/10.3390/molecules26041195
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author Valachová, Katarína
Šoltés, Ladislav
author_facet Valachová, Katarína
Šoltés, Ladislav
author_sort Valachová, Katarína
collection PubMed
description Chitosan is industrially acquired by the alkaline N-deacetylation of chitin. Chitin belongs to the β-N-acetyl-glucosamine polymers, providing structure, contrary to α-polymers, which provide food and energy. Another β-polymer providing structure is hyaluronan. A lot of studies have been performed on chitosan to explore its industrial use. Since chitosan is biodegradable, non-toxic, bacteriostatic, and fungistatic, it has numerous applications in medicine. Hyaluronan, one of the major structural components of the extracellular matrix in vertebrate tissues, is broadly exploited in medicine as well. This review summarizes the main areas where these two biopolymers have an impact. The reviewed areas mostly cover most medical applications, along with non-medical applications, such as cosmetics.
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spelling pubmed-79268412021-03-04 Versatile Use of Chitosan and Hyaluronan in Medicine † Valachová, Katarína Šoltés, Ladislav Molecules Review Chitosan is industrially acquired by the alkaline N-deacetylation of chitin. Chitin belongs to the β-N-acetyl-glucosamine polymers, providing structure, contrary to α-polymers, which provide food and energy. Another β-polymer providing structure is hyaluronan. A lot of studies have been performed on chitosan to explore its industrial use. Since chitosan is biodegradable, non-toxic, bacteriostatic, and fungistatic, it has numerous applications in medicine. Hyaluronan, one of the major structural components of the extracellular matrix in vertebrate tissues, is broadly exploited in medicine as well. This review summarizes the main areas where these two biopolymers have an impact. The reviewed areas mostly cover most medical applications, along with non-medical applications, such as cosmetics. MDPI 2021-02-23 /pmc/articles/PMC7926841/ /pubmed/33672365 http://dx.doi.org/10.3390/molecules26041195 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Valachová, Katarína
Šoltés, Ladislav
Versatile Use of Chitosan and Hyaluronan in Medicine †
title Versatile Use of Chitosan and Hyaluronan in Medicine †
title_full Versatile Use of Chitosan and Hyaluronan in Medicine †
title_fullStr Versatile Use of Chitosan and Hyaluronan in Medicine †
title_full_unstemmed Versatile Use of Chitosan and Hyaluronan in Medicine †
title_short Versatile Use of Chitosan and Hyaluronan in Medicine †
title_sort versatile use of chitosan and hyaluronan in medicine †
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926841/
https://www.ncbi.nlm.nih.gov/pubmed/33672365
http://dx.doi.org/10.3390/molecules26041195
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