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PARP Traps Rescue the Pro-Inflammatory Response of Human Macrophages in the In Vitro Model of LPS-Induced Tolerance

Secondary infections cause sepsis that lead to patient disability or death. Contact of macrophages with bacterial components (such as lipopolysaccharide—LPS) activates the intracellular signaling pathway downstream of Toll-like receptors (TLR), which initiate an immune proinflammatory response. Howe...

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Detalles Bibliográficos
Autores principales:	Pietrzak, Julita, Gronkowska, Karolina, Robaszkiewicz, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926882/ https://www.ncbi.nlm.nih.gov/pubmed/33671709 http://dx.doi.org/10.3390/ph14020170

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