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Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India

In many parts of the world, including in India, pharmacist roles in antimicrobial stewardship (AMS) programmes remain unexplored. We describe the evolution and effect of the role of adding clinical pharmacists to a multidisciplinary AMS at a tertiary care teaching hospital in Kerala, India. Through...

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Autores principales: Nampoothiri, Vrinda, Sudhir, Akkulath Sangita, Joseph, Mariam Varsha, Mohamed, Zubair, Menon, Vidya, Charani, Esmita, Singh, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926893/
https://www.ncbi.nlm.nih.gov/pubmed/33672095
http://dx.doi.org/10.3390/antibiotics10020220
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author Nampoothiri, Vrinda
Sudhir, Akkulath Sangita
Joseph, Mariam Varsha
Mohamed, Zubair
Menon, Vidya
Charani, Esmita
Singh, Sanjeev
author_facet Nampoothiri, Vrinda
Sudhir, Akkulath Sangita
Joseph, Mariam Varsha
Mohamed, Zubair
Menon, Vidya
Charani, Esmita
Singh, Sanjeev
author_sort Nampoothiri, Vrinda
collection PubMed
description In many parts of the world, including in India, pharmacist roles in antimicrobial stewardship (AMS) programmes remain unexplored. We describe the evolution and effect of the role of adding clinical pharmacists to a multidisciplinary AMS at a tertiary care teaching hospital in Kerala, India. Through effective leadership, multidisciplinary AMS (February 2016) and antitubercular therapy (ATT) stewardship programmes (June 2017) were established. Clinical pharmacists were introduced as core members of the programmes, responsible for the operational delivery of key stewardship interventions. Pharmacy-led audit and feedback monitored the appropriateness of antimicrobial prescriptions and compliance to AMS/ATT recommendations. Between February 2016 and January 2017, 56% (742/1326) of antimicrobial prescriptions were appropriate, and 54% (318/584) of recommendations showed compliance. By the third year of the AMS, appropriateness increased to 80% (1752/2190), and compliance to the AMS recommendations to 70% (227/325). The appropriateness of ATT prescriptions increased from a baseline of 61% (95/157) in the first year, to 72% (62/86, June 2018–February 2019). The compliance to ATT recommendations increased from 42% (25/60) to 58% (14/24). Such a model can be effective in implementing sustainable change in low- and middle-income countries (LMICs) such as India, where the shortage of infectious disease physicians is a major impediment to the implementation and sustainability of AMS programmes.
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spelling pubmed-79268932021-03-04 Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India Nampoothiri, Vrinda Sudhir, Akkulath Sangita Joseph, Mariam Varsha Mohamed, Zubair Menon, Vidya Charani, Esmita Singh, Sanjeev Antibiotics (Basel) Article In many parts of the world, including in India, pharmacist roles in antimicrobial stewardship (AMS) programmes remain unexplored. We describe the evolution and effect of the role of adding clinical pharmacists to a multidisciplinary AMS at a tertiary care teaching hospital in Kerala, India. Through effective leadership, multidisciplinary AMS (February 2016) and antitubercular therapy (ATT) stewardship programmes (June 2017) were established. Clinical pharmacists were introduced as core members of the programmes, responsible for the operational delivery of key stewardship interventions. Pharmacy-led audit and feedback monitored the appropriateness of antimicrobial prescriptions and compliance to AMS/ATT recommendations. Between February 2016 and January 2017, 56% (742/1326) of antimicrobial prescriptions were appropriate, and 54% (318/584) of recommendations showed compliance. By the third year of the AMS, appropriateness increased to 80% (1752/2190), and compliance to the AMS recommendations to 70% (227/325). The appropriateness of ATT prescriptions increased from a baseline of 61% (95/157) in the first year, to 72% (62/86, June 2018–February 2019). The compliance to ATT recommendations increased from 42% (25/60) to 58% (14/24). Such a model can be effective in implementing sustainable change in low- and middle-income countries (LMICs) such as India, where the shortage of infectious disease physicians is a major impediment to the implementation and sustainability of AMS programmes. MDPI 2021-02-23 /pmc/articles/PMC7926893/ /pubmed/33672095 http://dx.doi.org/10.3390/antibiotics10020220 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nampoothiri, Vrinda
Sudhir, Akkulath Sangita
Joseph, Mariam Varsha
Mohamed, Zubair
Menon, Vidya
Charani, Esmita
Singh, Sanjeev
Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title_full Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title_fullStr Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title_full_unstemmed Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title_short Mapping the Implementation of a Clinical Pharmacist-Driven Antimicrobial Stewardship Programme at a Tertiary Care Centre in South India
title_sort mapping the implementation of a clinical pharmacist-driven antimicrobial stewardship programme at a tertiary care centre in south india
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926893/
https://www.ncbi.nlm.nih.gov/pubmed/33672095
http://dx.doi.org/10.3390/antibiotics10020220
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