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Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production

Macroalgae are sources of bioactive compounds that are interesting from both a chemical and a medical point of view. Although their use in biomedicine has increased significantly in recent years, tests conducted to date have been mostly related to species from temperate latitudes, with the potential...

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Autores principales: González-Ballesteros, N., Rodríguez-Argüelles, M. C., Lastra-Valdor, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926919/
https://www.ncbi.nlm.nih.gov/pubmed/33672102
http://dx.doi.org/10.3390/molecules26041182
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author González-Ballesteros, N.
Rodríguez-Argüelles, M. C.
Lastra-Valdor, M.
author_facet González-Ballesteros, N.
Rodríguez-Argüelles, M. C.
Lastra-Valdor, M.
author_sort González-Ballesteros, N.
collection PubMed
description Macroalgae are sources of bioactive compounds that are interesting from both a chemical and a medical point of view. Although their use in biomedicine has increased significantly in recent years, tests conducted to date have been mostly related to species from temperate latitudes, with the potential application of Antarctic biodiversity being minor. The wide variety of algae species present on Antarctic coastal areas can be a source of new antioxidants. Bearing this in mind, the brown macroalgae Desmarestia antarctica (DA) and the red Iridaea cordata (IC) were selected for the preparation of aqueous extracts with the aim of analyzing their antioxidant activity. This analysis was performed by determining reducing power, total phenolic content, and 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity. Furthermore, both extracts were employed to synthesize gold and silver nanoparticles. The nanomaterials were fully characterized by means of UV-Visible spectroscopy, transmission electron microscopy, Z potential measurements, and Fourier transform infrared spectroscopy, which confirmed the formation of stable, spherical nanoparticles with mean diameters of 13.7 ± 3.1 and 17.5 ± 3.7 nm for Ag@DA and Ag@IC and 12.6 ± 1.9 and 12.3 ± 1.6 nm for Au@DA and Au@IC. Antioxidant assays were performed after the synthesis of the nanomaterials to evaluate their possible synergistic effect with the extracts. The results suggest that polysaccharides and proteins may play a key role in the process of reduction and stabilization. Finally, for the sake of comparison, the results obtained for the Antarctic macroalgae Desmarestia menziesii and Palmaria decipiens have also been considered in the present work.
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spelling pubmed-79269192021-03-04 Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production González-Ballesteros, N. Rodríguez-Argüelles, M. C. Lastra-Valdor, M. Molecules Article Macroalgae are sources of bioactive compounds that are interesting from both a chemical and a medical point of view. Although their use in biomedicine has increased significantly in recent years, tests conducted to date have been mostly related to species from temperate latitudes, with the potential application of Antarctic biodiversity being minor. The wide variety of algae species present on Antarctic coastal areas can be a source of new antioxidants. Bearing this in mind, the brown macroalgae Desmarestia antarctica (DA) and the red Iridaea cordata (IC) were selected for the preparation of aqueous extracts with the aim of analyzing their antioxidant activity. This analysis was performed by determining reducing power, total phenolic content, and 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity. Furthermore, both extracts were employed to synthesize gold and silver nanoparticles. The nanomaterials were fully characterized by means of UV-Visible spectroscopy, transmission electron microscopy, Z potential measurements, and Fourier transform infrared spectroscopy, which confirmed the formation of stable, spherical nanoparticles with mean diameters of 13.7 ± 3.1 and 17.5 ± 3.7 nm for Ag@DA and Ag@IC and 12.6 ± 1.9 and 12.3 ± 1.6 nm for Au@DA and Au@IC. Antioxidant assays were performed after the synthesis of the nanomaterials to evaluate their possible synergistic effect with the extracts. The results suggest that polysaccharides and proteins may play a key role in the process of reduction and stabilization. Finally, for the sake of comparison, the results obtained for the Antarctic macroalgae Desmarestia menziesii and Palmaria decipiens have also been considered in the present work. MDPI 2021-02-23 /pmc/articles/PMC7926919/ /pubmed/33672102 http://dx.doi.org/10.3390/molecules26041182 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
González-Ballesteros, N.
Rodríguez-Argüelles, M. C.
Lastra-Valdor, M.
Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title_full Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title_fullStr Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title_full_unstemmed Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title_short Evaluation of the Antioxidant Capacities of Antarctic Macroalgae and Their Use for Nanoparticles Production
title_sort evaluation of the antioxidant capacities of antarctic macroalgae and their use for nanoparticles production
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926919/
https://www.ncbi.nlm.nih.gov/pubmed/33672102
http://dx.doi.org/10.3390/molecules26041182
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