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Aerosolized Exposure to H5N1 Influenza Virus Causes Less Severe Disease Than Infection via Combined Intrabronchial, Oral, and Nasal Inoculation in Cynomolgus Macaques

Infection with highly pathogenic avian H5N1 influenza virus in humans often leads to severe respiratory disease with high mortality. Experimental infection in non-human primates can provide additional insight into disease pathogenesis. However, such a model should recapitulate the disease symptoms o...

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Detalles Bibliográficos
Autores principales: Mooij, Petra, Stammes, Marieke A., Mortier, Daniella, Fagrouch, Zahra, van Driel, Nikki, Verschoor, Ernst J., Kondova, Ivanela, Bogers, Willy M. J. M., Koopman, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7926951/
https://www.ncbi.nlm.nih.gov/pubmed/33671829
http://dx.doi.org/10.3390/v13020345