Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes

Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). There is limited knowledge about molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Madani, Aisha Y., Majeed, Yasser, Abdesselem, Houari B., Agha, Maha V., Vakayil, Muneera, Sukhun, Nour K. Al, Halabi, Najeeb M., Kumar, Pankaj, Hayat, Shahina, Elrayess, Mohamed A., Rafii, Arash, Suhre, Karsten, Mazloum, Nayef A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927067/
https://www.ncbi.nlm.nih.gov/pubmed/33672392
http://dx.doi.org/10.3390/antiox10020334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927067/
https://www.ncbi.nlm.nih.gov/pubmed/33672392
http://dx.doi.org/10.3390/antiox10020334

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