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Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes
Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). There is limited knowledge about molecular mechanisms...
Autores principales: | Madani, Aisha Y., Majeed, Yasser, Abdesselem, Houari B., Agha, Maha V., Vakayil, Muneera, Sukhun, Nour K. Al, Halabi, Najeeb M., Kumar, Pankaj, Hayat, Shahina, Elrayess, Mohamed A., Rafii, Arash, Suhre, Karsten, Mazloum, Nayef A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927067/ https://www.ncbi.nlm.nih.gov/pubmed/33672392 http://dx.doi.org/10.3390/antiox10020334 |
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