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PTP-3 phosphatase promotes intramolecular folding of SYD-2 to inactivate kinesin-3 UNC-104 in neurons

UNC-104 is the Caenorhabditis elegans homolog of kinesin-3 KIF1A known for its fast shuffling of synaptic vesicle protein transport vesicles in axons. SYD-2 is the homolog of liprin-α in C. elegans known to activate UNC-104; however, signals that trigger SYD-2 binding to the motor remain unknown. Be...

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Detalles Bibliográficos
Autores principales:	Muniesh, Muthaiyan Shanmugam, Barmaver, Syed Nooruzuha, Huang, Hsin-Yi, Bayansan, Odvogmed, Wagner, Oliver Ingvar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927192/ https://www.ncbi.nlm.nih.gov/pubmed/33147118 http://dx.doi.org/10.1091/mbc.E19-10-0591

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