Guanine nucleotide binding protein like-1 (GNL1) promotes cancer cell proliferation and survival through AKT/p21 (CIP1) signaling cascade

Human guanine nucleotide binding protein like 1 (GNL1) is an evolutionary conserved putative nucleolar GTPase belonging to the HSR1_MMR1 subfamily of GTPases. GNL1 was found to be highly up-regulated in various cancers. Here, we report for the first time that GNL1 inhibits apoptosis by modulating th...

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Detalles Bibliográficos
Autores principales: Krishnan, Rehna, Murugiah, Mariappan, Lakshmi,, Naga Padma, Mahalingam, Sundarasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927199/
https://www.ncbi.nlm.nih.gov/pubmed/33147101
http://dx.doi.org/10.1091/mbc.E20-04-0267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927199/
https://www.ncbi.nlm.nih.gov/pubmed/33147101
http://dx.doi.org/10.1091/mbc.E20-04-0267

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