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Isolated downregulation of HCN2 in ventricles of rats with streptozotocin-induced diabetic cardiomyopathy

BACKGROUND: In spite of disrupted repolarization of diabetic heart, some studies report less tendency of diabetic heart to develop ventricular arrhythmias suggesting effective compensatory mechanism. We hypothesized that myocardial alterations in HCN2 and HCN4 channels occur under hyperglycaemia. ME...

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Detalles Bibliográficos
Autores principales:	Hadova, Katarina, Kralova, Eva, Doka, Gabriel, Bies Pivackova, Lenka, Kmecova, Zuzana, Krenek, Peter, Klimas, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927235/ https://www.ncbi.nlm.nih.gov/pubmed/33653265 http://dx.doi.org/10.1186/s12872-021-01929-3

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