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Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is among the malignancies with the highest mortality. The key regulators and their interactive network in HCC pathogenesis remain unclear. Along with genetic mutations, aberrant epigenetic paradigms, including deregulated microRNAs (miRNAs), exer...

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Detalles Bibliográficos
Autores principales:	Zhao, Junlong, Li, Huichen, Zhao, Shoujie, Wang, Enxin, Zhu, Jun, Feng, Dayun, Zhu, Yejing, Dou, Weijia, Fan, Qingling, Hu, Jie, Jia, Lintao, Liu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927270/ https://www.ncbi.nlm.nih.gov/pubmed/33658044 http://dx.doi.org/10.1186/s12943-021-01343-5

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