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FBW7 suppresses ovarian cancer development by targeting the N(6)-methyladenosine binding protein YTHDF2

BACKGROUND: The tumor suppressor FBW7 is the substrate recognition component of the SCF E3-ubiquitin ligase complex that mediates proteolytic degradation of various oncogenic proteins. However, the role of FBW7 in ovarian cancer progression remains inadequately understood. METHODS: IP-MASS, co-IP, i...

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Detalles Bibliográficos
Autores principales:	Xu, Fei, Li, Jiajia, Ni, Mengdong, Cheng, Jingyi, Zhao, Haiyun, Wang, Shanshan, Zhou, Xiang, Wu, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927415/ https://www.ncbi.nlm.nih.gov/pubmed/33658012 http://dx.doi.org/10.1186/s12943-021-01340-8

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