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Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance
White adipose tissues (WAT) play crucial roles in maintaining whole-body energy homeostasis, and their dysfunction can contribute to hepatic insulin resistance and type 2 diabetes mellitus (T2DM). However, the mechanisms underlying these alterations remain unknown. By analyzing the transcriptome lan...
Autores principales: | He, Feng, Huang, Yanrui, Song, Zhi, Zhou, Huanjiao Jenny, Zhang, Haifeng, Perry, Rachel J., Shulman, Gerald I., Min, Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927432/ https://www.ncbi.nlm.nih.gov/pubmed/33315085 http://dx.doi.org/10.1084/jem.20201416 |
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