SPECT/CT with (99m)Tc labelled heat-denatured erythrocyte to detect thoracic and abdominal splenic tissue

Scintigraphy with (99m)Tc labelled heat-denatured erythrocyte (DRBC) allows non invasive diagnosis of heterotopic splenic tissue implantation (splenosis) following splenic trauma or surgery. Single-photon emission computed tomography (SPECT) combined with computed tomography (CT) improves diagnostic...

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Detalles Bibliográficos
Autores principales: Graziani, Tiziano, Baldari, Giorgio, Sammartano, Antonino, Scarlattei, Maura, Migliari, Silvia, Pescarenico, Giovanna M., Cidda, Carla, Bola, Stefano, Ruffini, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927460/
https://www.ncbi.nlm.nih.gov/pubmed/33525300
http://dx.doi.org/10.23750/abm.v91i4.9270
Descripción
Sumario:Scintigraphy with (99m)Tc labelled heat-denatured erythrocyte (DRBC) allows non invasive diagnosis of heterotopic splenic tissue implantation (splenosis) following splenic trauma or surgery. Single-photon emission computed tomography (SPECT) combined with computed tomography (CT) improves diagnostic accuracy of planar imaging through a more precise localization of functional findings. We report about two cases of splenosis occurring many years after splenectomy. (99M)Tc-DCRBC scintigraphy was used for differential diagnosis of metastatic disease in one case and to assess an incidental finding at bone scan in the second one. SPECT/CT increased specificity of planar imaging, expecially revealing combined (thoracic and abdominal) splenosis. (www.actabiomedica.it)

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