Cargando…

The role of angiotensin-converting enzyme 2 in COVID-19 induced lung injury

The novel coronavirus disease (COVID-19) has affected people around the world both physically and psychologically. As result, developing a coronavirus-specific vaccine and/or therapeutics is now a top priority for public health agencies. Since our findings of COVID-19 are relatively new, the current...

Descripción completa

Detalles Bibliográficos
Autores principales: Torabi, Sara, Bahreini, Farbod, Rezaei, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927558/
https://www.ncbi.nlm.nih.gov/pubmed/33525252
http://dx.doi.org/10.23750/abm.v91i4.10159
Descripción
Sumario:The novel coronavirus disease (COVID-19) has affected people around the world both physically and psychologically. As result, developing a coronavirus-specific vaccine and/or therapeutics is now a top priority for public health agencies. Since our findings of COVID-19 are relatively new, the current knowledge about the molecular mechanism involved in pathogenicity and virulence of the novel coronavirus is not advanced. Understanding angiotensin-converting enzyme 2 (ACE2), the receptor for the coronavirus, is significantly important. To better illustrate the role of ACE2 in the severity of COVID-19 and the impact of currently used drugs on this receptor, this paper briefly reviews newly published articles in this regard. (www.actabiomedica.it)