Cargando…
A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects
The generation of structurally standardized human pluripotent stem cell (hPSC)‐derived neural embryonic tissues has the potential to model genetic and environmental mediators of early neurodevelopmental defects. Current neural patterning systems have so far focused on directing cell fate specificati...
Autores principales: | Sahni, Geetika, Chang, Shu‐Yung, Meng, Jeremy Teo Choon, Tan, Jerome Zu Yao, Fatien, Jean Jacques Clement, Bonnard, Carine, Utami, Kagistia Hana, Chan, Puck Wee, Tan, Thong Teck, Altunoglu, Umut, Kayserili, Hülya, Pouladi, Mahmoud, Reversade, Bruno, Toh, Yi‐Chin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927627/ https://www.ncbi.nlm.nih.gov/pubmed/33717833 http://dx.doi.org/10.1002/advs.202001100 |
Ejemplares similares
-
A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects
por: Sahni, Geetika, et al.
Publicado: (2021) -
A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling
por: Bonnard, Carine, et al.
Publicado: (2020) -
A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability
por: Chia, Poh Hui, et al.
Publicado: (2018) -
Pallister-Killian syndrome: clinical, cytogenetic and molecular findings in 15 cases
por: Karaman, Birsen, et al.
Publicado: (2018) -
Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization
por: Cain, Corey J., et al.
Publicado: (2016)