Cargando…

Cardiac MyBP-C phosphorylation regulates the Frank–Starling relationship in murine hearts

The Frank–Starling relationship establishes that elevated end-diastolic volume progressively increases ventricular pressure and stroke volume in healthy hearts. The relationship is modulated by a number of physiological inputs and is often depressed in human heart failure. Emerging evidence suggests...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hanft, Laurin M., Fitzsimons, Daniel P., Hacker, Timothy A., Moss, Richard L., McDonald, Kerry S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927661/ https://www.ncbi.nlm.nih.gov/pubmed/33646280 http://dx.doi.org/10.1085/jgp.202012770

Ejemplares similares

MyBP-C: one protein to govern them all
por: Heling, L. W. H. J., et al.
Publicado: (2020)

Effect of MyBP-C Binding to Actin on Contractility in Heart Muscle
por: Kulikovskaya, Irina, et al.
Publicado: (2003)

A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation
por: Toepfer, Christopher N., et al.
Publicado: (2016)

Cardiac thin filament regulation and the Frank–Starling mechanism
por: Kobirumaki-Shimozawa, Fuyu, et al.
Publicado: (2014)

Understanding the Organisation and Role of Myosin Binding Protein C in Normal Striated Muscle by Comparison with MyBP-C Knockout Cardiac Muscle
por: Luther, Pradeep K., et al.
Publicado: (2008)

Simulation of the Frank-Starling Law of the Heart
por: Ribarič, Samo, et al.
Publicado: (2012)

Lessons from the frank-starling curve
por: Bloria, Summit D
Publicado: (2021)

Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs
por: Song, Taejeong, et al.
Publicado: (2023)

Looking for the inflexion point of the Frank-Starling curve
por: Aya, HD, et al.
Publicado: (2013)

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction
por: De Lange, Willem J., et al.
Publicado: (2013)

cMyBP-C phosphorylation modulates the time-dependent slowing of unloaded shortening in murine skinned myocardium
por: Giles, Jasmine, et al.
Publicado: (2021)

Titin Determines the Frank-Starling Relation in Early Diastole
por: Helmes, Michiel, et al.
Publicado: (2003)

The Frank–Starling Law: a jigsaw of titin proportions
por: Sequeira, Vasco, et al.
Publicado: (2017)

Is it possible to obtain Frank–Starling curves in the intensive care unit?
por: Machado, FS, et al.
Publicado: (2003)

Titin and Troponin: Central Players in the Frank-Starling Mechanism of the Heart
por: Fukuda, Norio, et al.
Publicado: (2009)

The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif
Publicado: (1993)

Frank-Starling and Guyton together at bedside during a fluid challenge
por: Aya, H, et al.
Publicado: (2012)

Revisiting Frank–Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (k (tr)) in a length‐dependent fashion
por: Toepfer, Christopher N., et al.
Publicado: (2016)

Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes
por: McDonald, Kerry S., et al.
Publicado: (2012)

Dystrophic cardiomyopathy: role of the cardiac myofilaments
por: George, Thomas G., et al.
Publicado: (2023)

Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless ‘Frank–Starling Gain’ index
por: Bollensdorff, Christian, et al.
Publicado: (2011)

N-terminal truncated cardiac troponin I enhances Frank-Starling response by increasing myofilament sensitivity to resting tension
por: Feng, Han-Zhong, et al.
Publicado: (2023)

Minimally invasive estimation of ventricular dead space volume through use of Frank-Starling curves
por: Davidson, Shaun, et al.
Publicado: (2017)

CARDIAC MYBP-C IN C57BL/6 MICE: THE EFFECTS OF AGE
por: Pinheiro, Amanda, et al.
Publicado: (2019)

Abnormal splicing in the N‐terminal variable region of cardiac troponin T impairs systolic function of the heart with preserved Frank‐Starling compensation
por: Feng, Han‐Zhong, et al.
Publicado: (2014)

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response
por: Scotcher, Jenna, et al.
Publicado: (2016)

Modulation of the Cardiomyocyte Contraction inside a Hydrostatic Pressure Bioreactor: In Vitro Verification of the Frank-Starling Law
por: Fassina, Lorenzo, et al.
Publicado: (2015)

Danicamtiv Enhances Systolic Function and Frank‐Starling Behavior at Minimal Diastolic Cost in Engineered Human Myocardium
por: Shen, Shi, et al.
Publicado: (2021)

Frank-Starling mechanism, fluid responsiveness, and length-dependent activation: Unravelling the multiscale behaviors with an in silico analysis
por: Kosta, Sarah, et al.
Publicado: (2021)

Implantation of cardiac defibrillator in an infant with hypertrophic cardiomyopathy and newly identified MYBP3 mutation
por: Güvenç, Osman, et al.
Publicado: (2020)

RLC phosphorylation amplifies Ca(2+) sensitivity of force in myocardium from cMyBP-C knockout mice
por: Turner, Kyrah L., et al.
Publicado: (2023)

The Role of the Frank–Starling Law in the Transduction of Cellular Work to Whole Organ Pump Function: A Computational Modeling Analysis
por: Niederer, Steven A., et al.
Publicado: (2009)

Cardiac efficiency and Starling's Law of the Heart
por: Han, June‐Chiew, et al.
Publicado: (2022)

Isolation and characterization of GtMYBP3 and GtMYBP4, orthologues of R2R3-MYB transcription factors that regulate early flavonoid biosynthesis, in gentian flowers
por: Nakatsuka, Takashi, et al.
Publicado: (2012)

Thin filament regulation of cardiac muscle power output: Implications for targets to improve human failing hearts
por: Hanft, Laurin M., et al.
Publicado: (2023)

Non-linearity of end-systolic pressure–volume relation in afterload increases is caused by an overlay of shortening deactivation and the Frank–Starling mechanism
por: Habigt, Moriz A., et al.
Publicado: (2021)

Inferring the Frank–Starling Curve From Simultaneous Venous and Arterial Doppler: Measurements From a Wireless, Wearable Ultrasound Patch
por: Kenny, Jon-Émile S., et al.
Publicado: (2021)

Regulatory mechanism of length-dependent activation in skinned porcine ventricular muscle: role of thin filament cooperative activation in the Frank-Starling relation
por: Terui, Takako, et al.
Publicado: (2010)

Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts
por: McDonald, Kerry S., et al.
Publicado: (2020)

A Non-Invasive Physiological Control System of a Rotary Blood Pump Based on Preload Sensitivity: Use of Frank–Starling-Like Mechanism
por: Wang, Fangqun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i9m4ngop5a94qt8dv6qotjsvl7