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Secretion of and Self-Resistance to the Novel Fibupeptide Antimicrobial Lugdunin by Distinct ABC Transporters in Staphylococcus lugdunensis
Lugdunin is the first reported nonribosomally synthesized antibiotic from human microbiomes. Its production by the commensal Staphylococcus lugdunensis eliminates the pathogen Staphylococcus aureus from human nasal microbiomes. The cycloheptapeptide lugdunin is the founding member of the new class o...
Autores principales: | Krauss, Sophia, Zipperer, Alexander, Wirtz, Sebastian, Saur, Julian, Konnerth, Martin C., Heilbronner, Simon, Torres Salazar, Benjamin O., Grond, Stephanie, Krismer, Bernhard, Peschel, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927808/ https://www.ncbi.nlm.nih.gov/pubmed/33106269 http://dx.doi.org/10.1128/AAC.01734-20 |
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