Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation

New antibiotics are urgently needed to address the mounting resistance challenge. In early drug discovery, one of the bottlenecks is the elucidation of targets and mechanisms. To accelerate antibiotic research, we provide a proteomic approach for the rapid classification of compounds into those with...

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Detalles Bibliográficos
Autores principales: Senges, Christoph H. R., Stepanek, Jennifer J., Wenzel, Michaela, Raatschen, Nadja, Ay, Ümran, Märtens, Yvonne, Prochnow, Pascal, Vázquez Hernández, Melissa, Yayci, Abdulkadir, Schubert, Britta, Janzing, Niklas B. M., Warmuth, Helen L., Kozik, Martin, Bongard, Jens, Alumasa, John N., Albada, Bauke, Penkova, Maya, Lukežič, Tadeja, Sorto, Nohemy A., Lorenz, Nicole, Miller, Reece G., Zhu, Bingyao, Benda, Martin, Stülke, Jörg, Schäkermann, Sina, Leichert, Lars I., Scheinpflug, Kathi, Brötz-Oesterhelt, Heike, Hertweck, Christian, Shaw, Jared T., Petković, Hrvoje, Brunel, Jean M., Keiler, Kenneth C., Metzler-Nolte, Nils, Bandow, Julia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927858/
https://www.ncbi.nlm.nih.gov/pubmed/33046497
http://dx.doi.org/10.1128/AAC.01373-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927858/
https://www.ncbi.nlm.nih.gov/pubmed/33046497
http://dx.doi.org/10.1128/AAC.01373-20

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