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Maintenance therapy for FLT3-ITD-mutated acute myeloid leukemia
FLT3-ITD is a constitutively activated variant of the FLT3 tyrosine kinase receptor. Its expression in acute myeloid leukemia (AML) is associated with a poor prognosis. Due to this, the development of tyrosine kinase inhibitors (TKI) blocking FLT3-ITD became a rational therapeutic concept. This revi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Fondazione Ferrata Storti
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927878/ https://www.ncbi.nlm.nih.gov/pubmed/33472354 http://dx.doi.org/10.3324/haematol.2019.240747 |