Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells

In ribosomopathies, the Diamond-Blackfan anemia (DBA) or 5q- syndrome, ribosomal protein (RP) genes are affected by mutation or deletion, resulting in bone marrow erythroid hypoplasia. Unbalanced production of ribosomal subunits leading to a limited ribosome cellular content regulates translation at...

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Detalles Bibliográficos
Autores principales: Boussaid, Ismael, Goff, Salomé Le, Floquet, Célia, Gautier, Emilie-Fleur, Raimbault, Anna, Viailly, Pierre-Julien, Al Dulaimi, Dina, Burroni, Barbara, Dusanter-Fourt, Isabelle, Hatin, Isabelle, Mayeux, Patrick, Cosson, Bertrand, Fontenay, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927886/
https://www.ncbi.nlm.nih.gov/pubmed/32327500
http://dx.doi.org/10.3324/haematol.2019.239970

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