Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect

Human intestinal epithelial cell line-6 (HIEC-6) cells and primary human hepatocytes (PHHs) were treated with 3-amidinophenylalanine-derived inhibitors of trypsin-like serine proteases for 24 hours. It was proven that treatment with MI-1900 and MI-1907 was tolerated up to 50 μM in HIEC-6. These inhi...

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Detalles Bibliográficos
Autores principales: Pászti-Gere, Erzsébet, Pomothy, Judit, Jerzsele, Ákos, Pilgram, Oliver, Steinmetzer, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928042/
https://www.ncbi.nlm.nih.gov/pubmed/33641565
http://dx.doi.org/10.1080/14756366.2021.1886093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928042/
https://www.ncbi.nlm.nih.gov/pubmed/33641565
http://dx.doi.org/10.1080/14756366.2021.1886093

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