Cargando…

hiPSCs for predictive modelling of neurodegenerative diseases: dreaming the possible

Human induced pluripotent stem cells (hiPSCs) were first generated in 2007, but the full translational potential of this valuable tool has yet to be realized. The potential applications of hiPSCs are especially relevant to neurology, as brain cells from patients are rarely available for research. hi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rivetti di Val Cervo, Pia, Besusso, Dario, Conforti, Paola, Cattaneo, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928200/ https://www.ncbi.nlm.nih.gov/pubmed/33658662 http://dx.doi.org/10.1038/s41582-021-00465-0

Ejemplares similares

Dopaminergic differentiation of schizophrenia hiPSCs
por: Hartley, Brigham J., et al.
Publicado: (2015)

Genetic Cardiomyopathies: The Lesson Learned from hiPSCs
por: My, Ilaria, et al.
Publicado: (2021)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs
por: Roberts, Brock, et al.
Publicado: (2019)

Fabrication of functional ameloblasts from hiPSCs for dental application
por: Kim, Ka-Hwa, et al.
Publicado: (2023)

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming
por: Ruiz, Sergio, et al.
Publicado: (2013)

Generation and Neuronal Differentiation of hiPSCs From Patients With Myotonic Dystrophy Type 2
por: Spitalieri, Paola, et al.
Publicado: (2018)

ASSURED-optimized CRISPR protocol for knockout/SNP knockin in hiPSCs
por: Ludwik, Katarzyna A., et al.
Publicado: (2023)

Effects of Simulated Microgravity on Wild Type and Marfan hiPSCs-Derived Embryoid Bodies
por: Spitalieri, Paola, et al.
Publicado: (2021)

Experimental Models to Study Autism Spectrum Disorders: hiPSCs, Rodents and Zebrafish
por: Pensado-López, Alba, et al.
Publicado: (2020)

Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease Modeling
por: Sun, Jing, et al.
Publicado: (2019)

Applying hiPSCs and Biomaterials Towards an Understanding and Treatment of Traumatic Brain Injury
por: Lacalle-Aurioles, María, et al.
Publicado: (2020)

PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs
por: Roudaut, Meryl, et al.
Publicado: (2021)

GCT-19. MODELING GERM CELL TUMORS WITH KIT MUTANT hiPSCs
por: Kuzuoka, Sakura, et al.
Publicado: (2020)

Exploiting hiPSCs in Leber's Hereditary Optic Neuropathy (LHON): Present Achievements and Future Perspectives
por: Peron, Camille, et al.
Publicado: (2021)

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives
por: Cao, Xu, et al.
Publicado: (2019)

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm
por: Sharma, Arun, et al.
Publicado: (2020)

Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration
por: Gao, Xin, et al.
Publicado: (2022)

Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs
por: Dias, Tiago P., et al.
Publicado: (2022)

Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants
por: Jin, Yinge, et al.
Publicado: (2023)

Two Different Therapeutic Approaches for SARS-CoV-2 in hiPSCs-Derived Lung Organoids
por: Spitalieri, Paola, et al.
Publicado: (2022)

Organoid factory: The recent role of the human induced pluripotent stem cells (hiPSCs) in precision medicine
por: Novelli, Giuseppe, et al.
Publicado: (2023)

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
por: Trudler, Dorit, et al.
Publicado: (2021)

FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons
por: Higelin, Julia, et al.
Publicado: (2016)

The Role of MicroRNAs in Early Chondrogenesis of Human Induced Pluripotent Stem Cells (hiPSCs)
por: Stelcer, Ewelina, et al.
Publicado: (2019)

PGC-1α promotes mitochondrial respiration and biogenesis during the differentiation of hiPSCs into cardiomyocytes
por: Zhou, Qin, et al.
Publicado: (2020)

Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment
por: Danoy, Mathieu, et al.
Publicado: (2021)

CRISPR-Cas9 in hiPSCs: A new era in personalized treatment for Stargardt disease
por: Kuntam, Soujanya, et al.
Publicado: (2023)

Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
por: Giovenale, Angela Maria Giada, et al.
Publicado: (2023)

Modeling Cardiomyopathies in a Dish: State-of-the-Art and Novel Perspectives on hiPSC-Derived Cardiomyocytes Maturation
por: Lodola, Francesco, et al.
Publicado: (2021)

hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer’s disease and potential therapeutics
por: TCW, Julia, et al.
Publicado: (2023)

Optimized Surface Markers for the Prospective Isolation of High-Quality hiPSCs using Flow Cytometry Selection
por: Abujarour, Ramzey, et al.
Publicado: (2013)

Platform for Induction and Maintenance of Transgene-free hiPSCs Resembling Ground State Pluripotent Stem Cells
por: Valamehr, Bahram, et al.
Publicado: (2014)

Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling
por: Xie, Yunyao, et al.
Publicado: (2017)

Comparison of multi-lineage differentiation of hiPSCs reveals novel miRNAs that regulate lineage specification
por: Li, Lu, et al.
Publicado: (2018)

Differentiation of Glial Cells From hiPSCs: Potential Applications in Neurological Diseases and Cell Replacement Therapy
por: Zheng, Wei, et al.
Publicado: (2018)

Zooming in on Cryopreservation of hiPSCs and Neural Derivatives: A Dual‐Center Study Using Adherent Vitrification
por: Kaindl, Johanna, et al.
Publicado: (2018)

Induction of Neural Crest Stem Cells From Bardet–Biedl Syndrome Patient Derived hiPSCs
por: Barrell, William B., et al.
Publicado: (2019)

Shh and Olig2 sequentially regulate oligodendrocyte differentiation from hiPSCs for the treatment of ischemic stroke
por: Xu, Jian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_he998h9qgo5qcra9t763bh0lou