Cargando…
Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D
Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ATP deficit; both factors are important in the memory decline showed during norm...
Autores principales: | Jara, Claudia, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928299/ https://www.ncbi.nlm.nih.gov/pubmed/33679286 http://dx.doi.org/10.3389/fnins.2020.586710 |
Ejemplares similares
-
Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus
por: Jara, Claudia, et al.
Publicado: (2018) -
Effect of Alcohol on Hippocampal-Dependent Plasticity and Behavior: Role of Glutamatergic Synaptic Transmission
por: Mira, Rodrigo G., et al.
Publicado: (2020) -
Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration
por: Pérez, María J., et al.
Publicado: (2018) -
Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
por: Serrano, Felipe G, et al.
Publicado: (2014) -
Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss
por: Olesen, Margrethe A., et al.
Publicado: (2020)