Mrc1-Dependent Chromatin Compaction Represses DNA Double-Stranded Break Repair by Homologous Recombination Upon Replication Stress

The coordination of DNA replication and repair is critical for the maintenance of genome stability. It has been shown that the Mrc1-mediated S phase checkpoint inhibits DNA double-stranded break (DSB) repair through homologous recombination (HR). How the replication checkpoint inhibits HR remains on...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Poyuan, Dong, Yang, Zhao, Jingyu, Zhou, Zhou, Li, Zhao, Wang, Yu, Li, Mengfei, Zhang, Xinghua, Chen, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928320/
https://www.ncbi.nlm.nih.gov/pubmed/33681209
http://dx.doi.org/10.3389/fcell.2021.630777

Ejemplares similares

Ejemplares similares