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DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization
Parkinson’s disease is a neurodegenerative disorder associated with misfolding and aggregation of α-synuclein as a hallmark protein. Two yeast strain collections comprising conditional alleles of essential genes were screened for the ability of each allele to reduce or improve yeast growth upon α-sy...
Autores principales: | Popova, Blagovesta, Wang, Dan, Pätz, Christina, Akkermann, Dagmar, Lázaro, Diana F., Galka, Dajana, Kolog Gulko, Miriam, Bohnsack, Markus T., Möbius, Wiebke, Bohnsack, Katherine E., Outeiro, Tiago F., Braus, Gerhard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928443/ https://www.ncbi.nlm.nih.gov/pubmed/33657088 http://dx.doi.org/10.1371/journal.pgen.1009407 |
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