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STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda

HIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfe...

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Autores principales: Chitneni, Pooja, Bwana, Mwebesa Bosco, Muyindike, Winnie, Owembabazi, Moran, Kalyebara, Paul Kato, Byamukama, Adolf, Mbalibulha, Yona, Smith, Patricia M., Hsu, Katherine K., Haberer, Jessica E., Kaida, Angela, Matthews, Lynn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928454/
https://www.ncbi.nlm.nih.gov/pubmed/33657120
http://dx.doi.org/10.1371/journal.pone.0246629
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author Chitneni, Pooja
Bwana, Mwebesa Bosco
Muyindike, Winnie
Owembabazi, Moran
Kalyebara, Paul Kato
Byamukama, Adolf
Mbalibulha, Yona
Smith, Patricia M.
Hsu, Katherine K.
Haberer, Jessica E.
Kaida, Angela
Matthews, Lynn T.
author_facet Chitneni, Pooja
Bwana, Mwebesa Bosco
Muyindike, Winnie
Owembabazi, Moran
Kalyebara, Paul Kato
Byamukama, Adolf
Mbalibulha, Yona
Smith, Patricia M.
Hsu, Katherine K.
Haberer, Jessica E.
Kaida, Angela
Matthews, Lynn T.
author_sort Chitneni, Pooja
collection PubMed
description HIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfected partner while minimizing HIV transmission risks. This study reflects an ongoing safer conception program embedded within a regional referral hospital HIV clinic in southwestern Uganda. We enrolled MLWH, planning for pregnancy with an HIV-uninfected partner and accessing safer conception care. Participants completed interviewer-administered questionnaires detailing socio-demographics, gender dynamics, and sexual history. Participants also completed STI laboratory screening for syphilis (immunochromatographic testing confirmed by rapid plasma reagin), and chlamydia, gonorrhea, trichomoniasis, and HIV-RNA via GeneXpert nucleic acid amplification testing. Bivariable associations of STI covariates were assessed using Fisher’s exact test. Among the 50 men who completed STI screening, median age was 33 (IQR 31–37) years, 13/50 (26%) had ≥2 sexual partners in the prior three months, and 46/50 (92%) had HIV-RNA <400 copies/mL. Overall, 11/50 (22%) had STIs: 16% active syphilis, 6% chlamydia. All participants initiated STI treatment. STI prevalence was associated with the use of threats/intimidation to coerce partners into sex (27% vs 3%; p = 0.03), although absolute numbers were small. We describe a 22% curable STI prevalence among a priority population at higher risk for transmission to partners and neonates. STI screening and treatment as a part of comprehensive sexual and reproductive healthcare should be integrated into HIV care to maximize the health of men, women, and children.
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spelling pubmed-79284542021-03-10 STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda Chitneni, Pooja Bwana, Mwebesa Bosco Muyindike, Winnie Owembabazi, Moran Kalyebara, Paul Kato Byamukama, Adolf Mbalibulha, Yona Smith, Patricia M. Hsu, Katherine K. Haberer, Jessica E. Kaida, Angela Matthews, Lynn T. PLoS One Research Article HIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfected partner while minimizing HIV transmission risks. This study reflects an ongoing safer conception program embedded within a regional referral hospital HIV clinic in southwestern Uganda. We enrolled MLWH, planning for pregnancy with an HIV-uninfected partner and accessing safer conception care. Participants completed interviewer-administered questionnaires detailing socio-demographics, gender dynamics, and sexual history. Participants also completed STI laboratory screening for syphilis (immunochromatographic testing confirmed by rapid plasma reagin), and chlamydia, gonorrhea, trichomoniasis, and HIV-RNA via GeneXpert nucleic acid amplification testing. Bivariable associations of STI covariates were assessed using Fisher’s exact test. Among the 50 men who completed STI screening, median age was 33 (IQR 31–37) years, 13/50 (26%) had ≥2 sexual partners in the prior three months, and 46/50 (92%) had HIV-RNA <400 copies/mL. Overall, 11/50 (22%) had STIs: 16% active syphilis, 6% chlamydia. All participants initiated STI treatment. STI prevalence was associated with the use of threats/intimidation to coerce partners into sex (27% vs 3%; p = 0.03), although absolute numbers were small. We describe a 22% curable STI prevalence among a priority population at higher risk for transmission to partners and neonates. STI screening and treatment as a part of comprehensive sexual and reproductive healthcare should be integrated into HIV care to maximize the health of men, women, and children. Public Library of Science 2021-03-03 /pmc/articles/PMC7928454/ /pubmed/33657120 http://dx.doi.org/10.1371/journal.pone.0246629 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Chitneni, Pooja
Bwana, Mwebesa Bosco
Muyindike, Winnie
Owembabazi, Moran
Kalyebara, Paul Kato
Byamukama, Adolf
Mbalibulha, Yona
Smith, Patricia M.
Hsu, Katherine K.
Haberer, Jessica E.
Kaida, Angela
Matthews, Lynn T.
STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title_full STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title_fullStr STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title_full_unstemmed STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title_short STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda
title_sort sti prevalence among men living with hiv engaged in safer conception care in rural, southwestern uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928454/
https://www.ncbi.nlm.nih.gov/pubmed/33657120
http://dx.doi.org/10.1371/journal.pone.0246629
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